Description

n-Allylpentobarbital is a specialized barbiturate derivative with a distinct allyl substitution at the N-position. This structural modification imparts unique pharmacological and chemical properties, making it a valuable intermediate for advanced research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents or the study of central nervous system (CNS) active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel barbiturate analogs and CNS-targeting compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of N-allyl substitution on pharmacokinetics and receptor binding.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Research: Employed in studies investigating the mechanisms of action of sedative-hypnotic agents and GABA receptor modulation.
• Fine Chemical Synthesis: Intermediate for the custom synthesis of more complex, target-specific molecules in contract research and manufacturing.

Basic Information

Product Name	n-Allylpentobarbital
CAS No.	99683-86-0
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	5-Ethyl-5-(1-methylbutyl)-1-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Allyl-5-(1-methylbutyl)barbituric acid; Allylpentobarbital; N-Allyl-5-ethyl-5-(1-methylbutyl)barbituric acid; NSC 163044
EINECS	Contact for details

Quality Control

Our n-Allylpentobarbital is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.