Description

4-Chloropyridine-2-Carboxamide is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive chlorinated heterocyclic scaffold for constructing complex molecules with precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific chloropyridine motifs.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for fine chemical and custom synthesis houses serving diverse R&D projects.

Basic Information

Product Name	4-Chloropyridine-2-Carboxamide
CAS No.	99586-65-9
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	2-Carbamoyl-4-chloropyridine; 4-Chloro-2-pyridinecarboxamide; 4-Chloropicolinamide; 4-Chloro-2-carbamoylpyridine; 4-Chloropyridine-2-carboxylic acid amide; Picolinamide, 4-chloro-; 99586-65-9
EINECS	Contact for details

Quality Control

Our 4-Chloropyridine-2-Carboxamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.