Description

2-Chloro-6-(trifluoromethyl)thiazolo[5,4-b]pyridine is a high-value, multi-functional heterocyclic building block. This compound is prized for its unique molecular architecture, which combines a halogenated thiazolopyridine core with a trifluoromethyl group, offering significant potential for modulating the physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly in the development of crop protection agents and pharmaceutical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a critical building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazolopyridine scaffold.
• Material Science Research: Used in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient character.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring complex, fluorinated heterocyclic systems.

Basic Information

Product Name	2-Chloro-6-(trifluoromethyl)thiazolo[5,4-b]pyridine
CAS No.	99520-99-7
Molecular Formula	C7H2ClF3N2S
Molecular Weight	238.62 g/mol
Synonyms	2-Chloro-6-(trifluoromethyl)[1,3]thiazolo[5,4-b]pyridine; Thiazolo[5,4-b]pyridine, 2-chloro-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2-chlorothiazolo[5,4-b]pyridine; 2-Chloro-6-trifluoromethylthiazolo[5,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(trifluoromethyl)thiazolo[5,4-b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.