Description

Vitamin D-C22 Acid is a key intermediate in the synthesis of biologically active vitamin D analogs and other high-value pharmaceutical compounds. This specialized chemical is critical for research and development in creating novel therapeutics targeting bone health, immune modulation, and cellular differentiation. It is primarily utilized by pharmaceutical manufacturers, advanced research institutions, and fine chemical synthesis companies.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of calcitriol, paricalcitol, and other vitamin D receptor agonists.
• Research & Development: Used in academic and industrial labs for studying vitamin D metabolism and developing new drug candidates.
• Fine Chemical Synthesis: Serves as a starting material or intermediate in multi-step organic syntheses for complex molecules.
• Biochemical Research: Employed in studies investigating the role of vitamin D derivatives in cellular processes and signaling pathways.
• Reference Standard: Can be used as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	Vitamin D-C22 Acid
CAS No.	99518-38-4
Molecular Formula	C28H44O3
Molecular Weight	428.65 g/mol
Synonyms	1α,25-Dihydroxyvitamin D3 23-carboxylic acid; 23-Carboxy-1,25-dihydroxyvitamin D3; 1,25-Dihydroxyvitamin D3-23-carboxylic acid; Calcitroic acid precursor; Vitamin D3 C-22 carboxylic acid; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our Vitamin D-C22 Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.