Description

Ethyl 3-Amino-6-Chloro-5-Cyano-2-Methylisonicotinate is a high-purity, multi-functional pyridine derivative serving as a critical advanced intermediate in organic synthesis. Its complex molecular structure, featuring amino, chloro, cyano, and ester functional groups, makes it a versatile building block for constructing sophisticated heterocyclic compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used to create complex chelating ligands for metal catalysts in asymmetric synthesis.
• Material Science Research: Intermediate for synthesizing functionalized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for proprietary synthesis projects.
• Academic & Industrial R&D: Used in research laboratories for methodological development and exploring new chemical entities.

Basic Information

Product Name	Ethyl 3-Amino-6-Chloro-5-Cyano-2-Methylisonicotinate
CAS No.	99421-19-9
Molecular Formula	C10H10ClN3O2
Molecular Weight	239.66 g/mol
Synonyms	Ethyl 3-Amino-6-chloro-5-cyano-2-methylpyridine-4-carboxylate; 3-Amino-6-chloro-5-cyano-2-methylisonicotinic acid ethyl ester; 2-Methyl-3-amino-6-chloro-5-cyanoisonicotinic acid ethyl ester; 4-Pyridinecarboxylic acid, 3-amino-6-chloro-5-cyano-2-methyl-, ethyl ester; 99421-19-9; Ethyl 3-amino-6-chloro-5-cyano-2-methyl-4-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-6-Chloro-5-Cyano-2-Methylisonicotinate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with ISO standards and the rigorous demands of pharmaceutical and agrochemical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound may be moisture-sensitive; ensure containers are sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.