Description

6-Chloro-5-(Trifluoromethyl)Pyridin-3-Amine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for creating compounds with tailored biological and physical properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients. Its reliable quality and consistent supply are fundamental for accelerating innovation in these high-tech sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, catalysts, and functionalized polymers used in electronic and advanced material applications.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating libraries of compounds for high-throughput screening.
• Fine Chemical Manufacturing: Acts as a versatile intermediate in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	6-Chloro-5-(Trifluoromethyl)Pyridin-3-Amine
CAS No.	99368-68-0
Molecular Formula	C6H4ClF3N2
Molecular Weight	196.56 g/mol
Synonyms	3-Amino-6-chloro-5-(trifluoromethyl)pyridine; 6-Chloro-5-trifluoromethylpyridin-3-amine; 5-(Trifluoromethyl)-6-chloropyridin-3-amine; 6-Chloro-5-(trifluoromethyl)-3-pyridinamine; 3-Pyridinamine, 6-chloro-5-(trifluoromethyl)-; 6-Chloro-5-trifluoromethyl-3-aminopyridine; 6-Chloro-α,α,α-trifluoro-3-pyridinamine
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-5-(Trifluoromethyl)Pyridin-3-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and relevant ISO standards guarantees a product suitable for demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.