Description

2-Chloro-5-Nitro-3-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique combination of halogen, nitro, and trifluoromethyl substituents. This compound is essential for the synthesis of complex molecules, offering chemists versatile sites for further functionalization and modification. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Chemical Biology & Proteomics: Employed in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents for life science research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-5-Nitro-3-(Trifluoromethyl)Pyridine
CAS No.	99368-67-9
Molecular Formula	C6H2ClF3N2O2
Molecular Weight	226.54 g/mol
Synonyms	3-(Trifluoromethyl)-2-chloro-5-nitropyridine; 2-Chloro-3-trifluoromethyl-5-nitropyridine; 5-Nitro-2-chloro-3-(trifluoromethyl)pyridine; Pyridine, 2-chloro-5-nitro-3-(trifluoromethyl)-; 2-Chloro-5-nitro-alpha,alpha,α-trifluoro-3-picoline
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Nitro-3-(Trifluoromethyl)Pyridine is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.