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Pyrrolidine, 1-(2-Fluoro-3-Hydroxy-4-Methyl-1-Oxopentyl)-, (R*,R*)- (9Ci) CAS NO 99343-24-5


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CAS No.:99343-24-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Pyrrolidine, 1-(2-Fluoro-3-Hydroxy-4-Methyl-1-Oxopentyl)-, (R*,R*)- (9Ci) is a specialized chiral pyrrolidine derivative, a key building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates fluorine and hydroxyl functional groups, enabling precise stereochemical control in complex molecule construction. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those targeting neurological and metabolic pathways.

Application

  • Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
  • Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is crucial for biological activity.
  • Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis, improving the efficiency of producing single-isomer compounds.
  • Chemical Research: Employed in academic and industrial R&D settings for methodological studies in fluoroorganic chemistry and the synthesis of complex natural product analogs.
  • Peptidomimetics Development: Its pyrrolidine core makes it a valuable scaffold for designing and synthesizing peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.

Basic Information

Item Details
Product Name Pyrrolidine, 1-(2-Fluoro-3-Hydroxy-4-Methyl-1-Oxopentyl)-, (R*,R*)- (9Ci)
CAS No. 99343-24-5
Molecular Formula C10H18FNO3
Molecular Weight 219.26 g/mol
Synonyms 1-[(2R,3R)-2-Fluoro-3-hydroxy-4-methyl-1-oxopentyl]pyrrolidine; (2R,3R)-2-Fluoro-3-hydroxy-4-methyl-1-pyrrolidin-1-ylpentan-1-one; 1-(2-Fluoro-3-hydroxy-4-methyl-1-oxopentyl)pyrrolidine, (R*,R*)-rel-; Fluorohydroxymethylpentanoyl pyrrolidine; Chiral fluorinated pyrrolidine ketone; Pyrrolidine derivative CAS 99343-24-5
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Quality Control

Every batch of our Pyrrolidine, 1-(2-Fluoro-3-Hydroxy-4-Methyl-1-Oxopentyl)-, (R*,R*)- (9Ci) undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to strict in-house quality standards suitable for research and process development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and specific tests is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% de
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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