Description

Pyrrolidine-2-Phosphonic Acid Phenyl Mono Ester is a specialized organophosphorus compound featuring a pyrrolidine backbone, which is of significant interest in advanced chemical synthesis and pharmaceutical research. This molecule serves as a key intermediate or building block for the development of novel bioactive compounds, particularly those targeting enzyme inhibition. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, agrochemicals, and the development of phosphonate-based ligands or catalysts. The compound's unique structure offers a versatile platform for creating molecules with tailored biological or catalytic activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly protease inhibitors or other enzyme-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new pharmacophores with enhanced biological activity.
• Agrochemical Development: Acts as a precursor in the creation of new herbicides, pesticides, or plant growth regulators with phosphonate moieties.
• Chemical Biology Probe: Employed in the design of molecular probes to study enzyme function and biochemical pathways.
• Catalyst & Ligand Synthesis: Utilized for developing chiral phosphonate-based ligands for asymmetric catalysis in fine chemical production.
• Peptidomimetic Research: Incorporated into peptide analogs to enhance stability, bioavailability, or receptor binding affinity.

Basic Information

Product Name	Pyrrolidine-2-Phosphonic Acid Phenyl Mono Ester
CAS No.	99305-82-5
Molecular Formula	C10H14NO3P
Molecular Weight	227.20 g/mol
Synonyms	Phenyl (2S)-1-phosphonopyrrolidine-2-carboxylate; (S)-Phenyl 1-phosphonopyrrolidine-2-carboxylate; 2-Pyrrolidinephosphonic acid phenyl monoester; L-Prolinol phosphate phenyl ester; Phosphoproline phenyl ester; Pyrrolidin-2-yl-phosphonic acid phenyl ester; (2S)-2-(Phenoxycarbonyl)pyrrolidin-1-yl]phosphonic acid
EINECS	Contact for details

Quality Control

Our Pyrrolidine-2-Phosphonic Acid Phenyl Mono Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.