Description

[1,1-Bicyclopropyl]-2-Carboxylicacid,2-Amino-,trans-(9Ci) is a specialized bicyclopropyl amino acid derivative, a high-value chiral building block in advanced organic synthesis. Its unique constrained bicyclic structure and functional groups make it a critical intermediate for constructing complex molecules with specific stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique bicyclic scaffold for enhanced activity and selectivity.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics: Incorporated into peptide analogs to induce specific conformational constraints, improving metabolic stability and binding affinity.
• Material Science Research: Explored as a monomer or building block for specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	[1,1-Bicyclopropyl]-2-Carboxylicacid,2-Amino-,trans-(9Ci)
CAS No.	99299-42-0
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	trans-2-Amino[1,1'-bicyclopropane]-2-carboxylic acid; (1R,2S)-2-Aminobicyclo[1.1.0]butane-2-carboxylic acid; Bicyclopropyl amino acid; 2-Aminobicyclo[1.1.0]butane-2-carboxylic acid, trans-; 2-Amino[1,1'-bicyclopropane]-2-carboxylic acid; (1S,2R)-rel-2-Aminobicyclo[1.1.0]butane-2-carboxylic acid; BCP-AA; 99299-42-0
EINECS	Contact for details

Quality Control

Our [1,1-Bicyclopropyl]-2-Carboxylicacid,2-Amino-,trans-(9Ci) is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, chiral purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.