Description

Interferon Alfa-2B is a highly purified, recombinant human protein belonging to the cytokine family of signaling molecules. This product is critical for its potent antiviral and immunomodulatory activities, making it a key active pharmaceutical ingredient (API) in therapeutic formulations. It is primarily utilized by the pharmaceutical and biotechnology industries for the research, development, and commercial production of targeted therapies.

Application

• Pharmaceutical API: Core ingredient in injectable formulations for the treatment of chronic hepatitis B and C, certain cancers (like hairy cell leukemia and melanoma), and other viral infections.
• Biopharmaceutical Research: Used as a critical reagent in cell culture studies, signaling pathway analysis, and immunology research to understand host defense mechanisms.
• Therapeutic Development: Serves as a reference standard or starting material for developing novel interferon-based therapies, including pegylated versions for improved pharmacokinetics.
• Diagnostic Manufacturing: Employed in the production of diagnostic kits and assays for monitoring immune response and disease progression.
• Cell Therapy & Regenerative Medicine: Investigated for use in ex-vivo cell conditioning and as a component in media for specialized cell culture applications.

Basic Information

Product Name	Interferon Alfa-2B
CAS No.	99210-65-8
Molecular Formula	C860H1353N227O255S9
Molecular Weight	Approx. 19,271 Da
Synonyms	Interferon α-2b; rIFN-α2b; Recombinant Human Interferon α-2b; IFN α-2b; Hu-IFN-alpha2b; Interferon alfa-2b (recombinant); IFN-α2b; INTRON A (Brand Name Reference)
EINECS	Contact for details

Quality Control

Our Interferon Alfa-2B is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and safety, meeting standards suitable for pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting specifications for purity (by HPLC), biological activity (in vitro cell-based assay), endotoxin levels, and related proteins.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized (freeze-dried) material at -20°C or below. Reconstituted solutions should be used immediately or stored at 2-8°C for short periods as validated. This product is hygroscopic (moisture-sensitive) and must be protected from humidity.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Purity (RP-HPLC)	≥ 98.0%
Biological Activity	≥ 2.0 x 108 IU/mg
Endotoxin	< 10 EU/mg
Moisture Content (KF)	≤ 3.0%
Related Proteins (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.