Description

2-(Piperidin-4-Ylsulfanyl)Pyridine Dihydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant interest in modern synthetic chemistry. Its core value lies in its unique molecular scaffold, which combines a piperidine ring linked via a thioether bridge to a pyridine moiety, making it a versatile precursor for the development of novel bioactive compounds. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential drug candidates targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs, especially for neurological targets.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing complex ligands used in catalysis and metal-organic frameworks.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Academic & Industrial R&D: Employed in synthetic organic chemistry laboratories for methodological development and novel compound synthesis.

Basic Information

Item	Details
Product Name	2-(Piperidin-4-Ylsulfanyl)Pyridine Dihydrochloride
CAS No.	99202-39-8
Molecular Formula	C10H16Cl2N2S
Molecular Weight	267.22 g/mol
Synonyms	2-[(4-Piperidinyl)thio]pyridine dihydrochloride; 2-(4-Piperidylsulfanyl)pyridine dihydrochloride; 4-[(Pyridin-2-yl)thio]piperidine dihydrochloride; 2-Piperidin-4-ylsulfanyl-pyridine dihydrochloride; 2-(Piperidin-4-ylthio)pyridine dihydrochloride; 2-(4-Piperidinylthio)pyridine dihydrochloride; 99202-39-8; 2-(Piperidin-4-Ylsulfanyl)Pyridine 2HCl
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-4-Ylsulfanyl)Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.