Description

1-Oxa-6-Azaspiro[2.5]Octane-2-Carboxylicacid,6-Methyl-,Ethylester(6Ci) is a high-value, spirocyclic heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural framework, which is pivotal in constructing complex molecular architectures with precise three-dimensional control. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting the central nervous system (CNS).
• Medicinal Chemistry Building Block: Used in fragment-based drug discovery and lead optimization to introduce spirocyclic motifs that can improve metabolic stability and binding affinity.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, or insecticides with new modes of action.
• Chemical Biology Probe Development: Utilized to create tool compounds for studying biological pathways and protein function.
• Academic & Contract Research: Employed in university and CRO settings for methodological studies in synthetic organic chemistry and heterocycle synthesis.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) engaged in producing bespoke fine chemicals for client projects.

Basic Information

Product Name	1-Oxa-6-Azaspiro[2.5]Octane-2-Carboxylicacid,6-Methyl-,Ethylester(6Ci)
CAS No.	99189-75-0
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	Ethyl 6-methyl-1-oxa-6-azaspiro[2.5]octane-2-carboxylate; 6-Methyl-1-oxa-6-azaspiro[2.5]octane-2-carboxylic acid ethyl ester; 1-Oxa-6-azaspiro[2.5]octane-2-carboxylic acid, 6-methyl-, ethyl ester; 99189-75-0; Ethyl 6-methyl-1-oxa-6-azaspiro[2.5]octane-2-carboxylate (6CI); Spiro[oxirane-2,2'-1,4-oxazepane]-5'-carboxylic acid, 4'-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our 1-Oxa-6-Azaspiro[2.5]Octane-2-Carboxylicacid,6-Methyl-,Ethylester(6Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.