Description

Norethisterone Acetate 3-Cyclopentylpropionate is a high-purity synthetic steroid derivative, specifically a prodrug form of norethisterone acetate. This compound is valued for its enhanced stability and controlled-release properties, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by research institutions and pharmaceutical manufacturers developing next-generation hormonal therapies and long-acting contraceptive formulations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel progestin-based active pharmaceutical ingredients (APIs).
• Hormone Therapy Research: Used in preclinical and clinical research for developing treatments for endometriosis, menopausal symptoms, and hormone-dependent cancers.
• Contraceptive Development: Serves as a precursor for long-acting injectable or implantable contraceptive agents due to its esterified structure.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: Utilized in studies investigating steroid receptor binding affinity and metabolic pathways.

Basic Information

Product Name	Norethisterone Acetate 3-Cyclopentylpropionate
CAS No.	99112-29-5
Molecular Formula	C28H38O4
Molecular Weight	438.60 g/mol
Synonyms	19-Norpregn-4-en-20-yn-3-one, 17-(acetyloxy)-, 3-(cyclopentylpropanoate); Norethindrone Acetate 3-Cyclopentylpropionate; 17α-Ethynyl-19-nortestosterone Acetate 3-Cyclopentylpropionate; Norethisterone Acetate Cyclopentylpropionate Ester; NET-A 3-CPP; 99112-29-5; Norethindrone Acetate 3-(3-Cyclopentylpropionate)
EINECS	Contact for details

Quality Control

Our Norethisterone Acetate 3-Cyclopentylpropionate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) with batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.