Description

Progesterone CAS NO 57-83-0 is a vital endogenous steroid hormone and a key intermediate in the biosynthesis of other steroid hormones. It is essential for regulating the menstrual cycle, supporting pregnancy, and maintaining the endometrium. This high-purity compound is critical for the pharmaceutical industry, particularly in the development and manufacturing of hormone replacement therapies, contraceptives, and other steroidal APIs.

Application

• Pharmaceutical Active Ingredient (API): Core component in hormone replacement therapy (HRT) products, contraceptive pills, and treatments for menstrual disorders.
• Steroid Intermediate: Key starting material or intermediate in the synthesis of other important steroid-based pharmaceuticals.
• Veterinary Medicine: Used in formulations for estrus synchronization and fertility management in livestock.
• Research & Development: Essential reference standard and biochemical tool in endocrinology, reproductive biology, and pharmacology research.
• Cosmetic & Nutraceutical Formulations: Incorporated into specialized topical formulations and dietary supplements, subject to regional regulatory compliance.

Basic Information

Product Name	Progesterone
CAS No.	57-83-0
Molecular Formula	C21H30O2
Molecular Weight	314.46 g/mol
Synonyms	Pregn-4-ene-3,20-dione; 4-Pregnene-3,20-dione; Corpus Luteum Hormone; Luteal Hormone; Luteosterone; Progestin; Progestogel; Utrogestan; Crinone; Prometrium; Gestone; Cyclogest; (8R,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
EINECS	200-350-6

Quality Control

Our Progesterone is manufactured under strict quality management systems. It is typically produced to meet or exceed relevant pharmacopeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including identification, assay, and impurity profiling. Certificates of Analysis (COA) are provided to ensure full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept tightly sealed after opening to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0%
Specific Rotation	+172° to +182° (c=1 in dioxane)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.