Description

3,5(10)-Triene-3,16-Diol, (16.Beta.)-Estra-1 is a high-purity steroid derivative and a key intermediate in advanced organic synthesis. This compound is valued for its defined stereochemistry and structural integrity, which are critical for producing consistent and reliable results in research and manufacturing. It serves as a vital building block for pharmaceutical R&D, particularly in the development of steroidal APIs, hormone analogs, and fine chemical products.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of steroidal active pharmaceutical ingredients (APIs) and hormone-based therapeutics.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex organic molecules with specific chiral centers.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Utilized in metabolic pathway studies and the development of diagnostic assays related to endocrine function.

Basic Information

Product Name	3,5(10)-Triene-3,16-Diol, (16.Beta.)-Estra-1
CAS No.	1225-58-7
Molecular Formula	C18H24O2
Molecular Weight	272.38 g/mol
Synonyms	16β-Hydroxyestra-1,3,5(10)-trien-3-ol; Estra-1,3,5(10)-triene-3,16β-diol; 16β-Estradiol; 16-Epiestriol; 16β-Hydroxyestrone; 3,16β-Dihydroxyestra-1,3,5(10)-triene
EINECS	Contact for details

Quality Control

Our 3,5(10)-Triene-3,16-Diol, (16.Beta.)-Estra-1 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.