Description

Promegestone CAS NO 34184-77-5 is a synthetic progestogen, a steroidal compound with high affinity and selectivity for the progesterone receptor. This compound is a critical intermediate and active pharmaceutical ingredient (API) in the development and manufacturing of advanced hormonal therapies. It is primarily utilized by pharmaceutical R&D laboratories and manufacturers specializing in women's health, oncology, and endocrinology. Its defined chemical structure ensures consistent biological activity, making it essential for producing reliable and effective therapeutic formulations.

Application

• Pharmaceutical Active Ingredient (API): Core component in the synthesis of prescription medications for hormone replacement therapy (HRT) and related treatments.
• Biomedical Research: Used as a reference standard and tool compound in preclinical studies to investigate progesterone receptor signaling and function.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the development of new steroidal drugs targeting gynecological and endocrine disorders.
• Clinical Diagnostics: Employed in the calibration and validation of diagnostic assays that measure progesterone activity or related biomarkers.
• Veterinary Pharmaceuticals: Applied in the formulation of hormonal treatments for reproductive management in animals.

Basic Information

Product Name	Promegestone
CAS No.	34184-77-5
Molecular Formula	C₂₂H₃₀O₃
Molecular Weight	342.47 g/mol
Synonyms	Promegestone; 17α-Methyl-19-norpregna-4,9-diene-3,20-dione; R-5020; 17α-Methyl-δ⁹-19-norprogesterone; NSC-118191; SH-582; 17α-Methyl-19-nor-4,9-pregnadiene-3,20-dione; (17α)-17-Methyl-19-norpregna-4,9-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our Promegestone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and GC. We provide full traceability and support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure quality and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. Keep the container tightly sealed after each use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.