Description

3-Cyano-5-Nitro-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate characterized by its cyano and nitro substituents on a benzoic acid ester backbone. This compound is critical for facilitating complex organic synthesis, particularly in the construction of advanced heterocyclic systems and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring a nitrile or nitro group for further functionalization.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its aromatic core provides structural diversity.
• Dye and Pigment Precursor: Serves as a starting material for synthesizing specialized azo dyes and organic pigments due to its reactive nitro and ester groups.
• Ligand and Catalyst Development: Employed in academic and industrial research to create novel ligands for metal catalysis and organocatalysts.
• Polymer Modification: Acts as a monomer or functionalizing agent for creating specialty polymers with specific thermal or chemical resistance properties.
• Chemical Research (R&D): A versatile reagent for methodological studies in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	3-Cyano-5-Nitro-Benzoic Acid Methyl Ester
CAS No.	99066-80-5
Molecular Formula	C9H6N2O4
Molecular Weight	206.16 g/mol
Synonyms	Methyl 3-Cyano-5-nitrobenzoate; 5-Nitroisophthalic Acid Monomethyl Ester Nitrile; Benzoic acid, 3-cyano-5-nitro-, methyl ester; Methyl 5-nitro-3-cyanobenzoate; 3-Cyano-5-nitrobenzoic acid methyl ester; 99066-80-5; Methyl 3-cyano-5-nitrobenzoate
EINECS	Contact for details

Quality Control

Our 3-Cyano-5-Nitro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.