Description

Ethyl 5-Acetyl-2-Pyridinecarboxylate is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both an acetyl and an ester group on the pyridine ring, makes it a valuable precursor for creating complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the synthesis of functionalized pyridine polymers or organic electronic materials.
• Chemical Research & Development: A versatile starting material for academic and industrial R&D focused on heterocyclic chemistry and method development.

Basic Information

Product Name	Ethyl 5-Acetyl-2-Pyridinecarboxylate
CAS No.	99060-45-4
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	5-Acetylpyridine-2-carboxylic acid ethyl ester; Ethyl 5-acetylpicolinate; 2-Pyridinecarboxylic acid, 5-acetyl-, ethyl ester; 5-Acetyl-2-pyridinecarboxylic acid ethyl ester; Ethyl 5-acetyl-2-pyridinecarboxylate; 99060-45-4; Ethyl 5-acetylpicolinate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Acetyl-2-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to consistent quality and traceability supports our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.