Description

Butanoic Acid, 2-[(Bicyclo[2.2.1]Hept-2-Ylcarbonyl)Amino]- is a specialized chiral building block featuring a norbornane (bicyclo[2.2.1]heptane) scaffold fused with an amino acid derivative. This compound matters for its unique three-dimensional structure, which is highly valuable in the design and synthesis of complex, bioactive molecules where spatial orientation is critical for function. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and as a precursor for novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the rigid norbornane structure can enhance binding specificity and environmental stability.
• Asymmetric Catalysis Ligand Precursor: The chiral center and functional groups make it a candidate for developing novel ligands used in asymmetric hydrogenation and other catalytic processes.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific stereochemical properties for advanced materials.
• Peptidomimetics Development: Acts as a constrained, non-natural amino acid analog in the design of peptide-like molecules with improved metabolic stability and potency.
• Chemical Biology Probes: Utilized in academic and industrial research to create molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Item	Details
Product Name	Butanoic Acid, 2-[(Bicyclo[2.2.1]Hept-2-Ylcarbonyl)Amino]-
CAS No.	99028-70-3
Molecular Formula	C13H19NO3
Molecular Weight	237.29 g/mol
Synonyms	2-[(2-Norbornanecarbonyl)amino]butanoic acid; 2-[(Bicyclo[2.2.1]heptane-2-carbonyl)amino]butyric acid; N-(2-Norbornylcarbonyl)-L-norvaline (stereoisomer specific); N-(Bicyclo[2.2.1]hept-2-ylcarbonyl)-2-aminobutanoic acid; Amino acid norbornane derivative; Norvaline norbornane amide; Chiral norbornane amino acid
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 2-[(Bicyclo[2.2.1]Hept-2-Ylcarbonyl)Amino]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.