Description

Iguratimod is a small molecule immunomodulatory agent with potent anti-inflammatory and disease-modifying properties. Its primary value lies in its targeted mechanism of action, which selectively inhibits the production of pro-inflammatory cytokines, offering a significant therapeutic advantage. This compound is essential for pharmaceutical R&D teams and manufacturers focused on developing advanced treatments for autoimmune disorders, particularly rheumatoid arthritis.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key active component in formulated drugs for autoimmune conditions.
• Rheumatoid Arthritis (RA) Treatment: Core application in the development and manufacturing of disease-modifying antirheumatic drugs (DMARDs).
• Biomedical Research: Critical reference standard and biochemical tool for studying immunology, cytokine signaling pathways, and inflammatory disease mechanisms.
• Preclinical & Clinical Development: Serves as a high-purity intermediate or finished API for toxicology studies and clinical trial material (CTM) production.
• Generic Drug Manufacturing: Sourcing of API for the production of generic versions of approved iguratimod-based medications.
• Dosage Form Development: Used in formulation studies for tablets, capsules, and other solid oral dosage forms.

Basic Information

Product Name	Iguratimod
CAS No.	123663-49-0
Molecular Formula	C₁₇H₁₄N₂O₂S
Molecular Weight	310.37 g/mol
Synonyms	T-614; 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one; 3-(Formylamino)-7-[(methylsulfonyl)amino]-6-phenoxy-4H-1-benzopyran-4-one; 3-FA-7-MSA-6-phenoxy-4H-1-benzopyran-4-one; Careram; Iremod
EINECS	Contact for details

Quality Control

Our Iguratimod is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and APIs. Quality is assured through comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods. A Certificate of Analysis (COA) is provided with each batch, detailing compliance with agreed specifications. We support development and commercial projects requiring standards consistent with GMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or a nitrogen atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.