Description

1-Boc-3-Piperidone is a versatile and high-purity protected piperidone derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a reactive ketone functionality while the Boc (tert-butoxycarbonyl) group offers orthogonal protection for the amine, enabling precise, multi-step synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs), complex natural products, and novel heterocyclic compounds. Its reliable quality and consistent performance make it a cornerstone for efficient and scalable process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various piperidine-based drug candidates, including kinase inhibitors, receptor antagonists, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides that incorporate the piperidine scaffold for enhanced biological activity.
• Organic Building Block: Employed in academic and industrial R&D for constructing complex molecular architectures through reactions like nucleophilic addition, reductive amination, and Grignard reactions.
• Peptidomimetics & PROTACs: Facilitates the creation of peptide mimics and Proteolysis Targeting Chimeras (PROTACs) by providing a rigid, functionalized heterocyclic core.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	1-Boc-3-Piperidone
CAS No.	98977-36-7
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-piperidone; 3-Oxo-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 3-oxopiperidine-1-carboxylate; 1-Boc-piperidin-3-one; N-Boc-3-piperidone; 3-Piperidone, 1-(1,1-dimethylethoxy)carbonyl]-; Boc-3-piperidone; N-tert-Butoxycarbonyl-3-piperidone
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Piperidone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.