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2-[(Azidoacetyl)Amino]-2-Deoxy-D-Glucopyranose 1,3,4,6-Tetraacetate CAS NO 98924-81-3
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CAS No.:98924-81-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-[(Azidoacetyl)Amino]-2-Deoxy-D-Glucopyranose 1,3,4,6-Tetraacetate is a key protected glycosyl azide derivative, serving as a versatile intermediate in advanced organic synthesis. Its core value lies in enabling the precise construction of complex carbohydrate-based molecules and glycoconjugates through click chemistry and other bioorthogonal reactions. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel drug candidates, bioconjugation probes, and materials for chemical biology.
Application
- Pharmaceutical Intermediate: Critical building block for the synthesis of glycosidase inhibitors, antiviral agents, and other bioactive carbohydrate mimetics.
- Bioconjugation & Click Chemistry: The azide functional group enables efficient, site-specific conjugation with alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling proteins, antibodies, and other biomolecules.
- Glycobiology Research: Used to prepare defined oligosaccharides, glycopeptides, and glycoarrays for studying carbohydrate-protein interactions and cell signaling.
- Material Science: Precursor for synthesizing functionalized polymers and surfaces with bioactive carbohydrate motifs.
- Diagnostic Reagent Development: Employed in the creation of fluorescent or chemiluminescent probes for cellular imaging and diagnostic assays.
- Chemical Biology Tool Development: Serves as a key reagent for metabolic glycan labeling and other techniques to probe biological systems.
Basic Information
| Product Name | 2-[(Azidoacetyl)Amino]-2-Deoxy-D-Glucopyranose 1,3,4,6-Tetraacetate |
| CAS No. | 98924-81-3 |
| Molecular Formula | C₁₆H₂₂N₄O₁₀ |
| Molecular Weight | 430.37 g/mol |
| Synonyms | 2-Deoxy-2-[(azidoacetyl)amino]-D-glucopyranose 1,3,4,6-tetraacetate; N-Azidoacetyl-D-glucosamine tetraacetate; 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose azidoacetyl derivative; GlcNAc(Ac)₄-N₃; Azidoacetylglucosamine tetraacetate; 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-(2-azidoacetamido)-β-D-glucopyranose; N-(Azidoacetyl)-β-D-glucosamine tetraacetate |
| EINECS | Contact for details |
Quality Control
Our 2-[(Azidoacetyl)Amino]-2-Deoxy-D-Glucopyranose 1,3,4,6-Tetraacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and traceability.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing desiccated at 2-8°C.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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