Description

2-Chloro-4-Methoxynicotinonitrile is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and methoxy substituents on the nitrile-functionalized pyridine ring, makes it an essential intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and enzyme inhibitors.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.

Basic Information

Product Name	2-Chloro-4-Methoxynicotinonitrile
CAS No.	98645-43-3
Molecular Formula	C7H5ClN2O
Molecular Weight	168.58 g/mol
Synonyms	2-Chloro-4-methoxypyridine-3-carbonitrile; 3-Cyano-2-chloro-4-methoxypyridine; 4-Methoxy-2-chloronicotinonitrile; 2-Chloro-4-methoxy-3-pyridinecarbonitrile; 98645-43-3; 2-Chloro-4-methoxynicotinonitrile; Nicotinonitrile, 2-chloro-4-methoxy-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methoxynicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.