Description

Interferon Alfa-2B is a highly purified recombinant protein belonging to the cytokine family, specifically a type I interferon. This product is critical for its potent antiviral, antiproliferative, and immunomodulatory activities, making it a cornerstone in advanced therapeutic development. It is essential for pharmaceutical manufacturers and research institutions engaged in the production of biologics, oncology treatments, and virology research. The compound is supplied under stringent quality controls to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Active Ingredient: Primary use in the formulation of injectable therapeutics for treating conditions such as chronic hepatitis B and C, certain cancers (e.g., hairy cell leukemia, melanoma), and genital warts.
• Oncology Research & Development: Used in preclinical and clinical studies to investigate its role in cancer immunotherapy and its synergistic effects with other agents.
• Virology and Antiviral Studies: Employed as a reference standard or active component in research aimed at understanding host antiviral defense mechanisms and developing new antiviral drugs.
• Biologics Manufacturing: Serves as a key intermediate or bulk drug substance in the GMP-compliant production of finished dosage forms (lyophilized powders or solutions).
• Cell Culture & Biomedical Research: Utilized in vitro to study signal transduction pathways (JAK-STAT), gene expression, and cellular immune responses.
• Diagnostic Reagent Production: Can be used in the development and calibration of immunoassays and diagnostic kits for interferon-related studies.

Basic Information

Product Name	Interferon Alfa-2B
CAS No.	98530-12-2
Molecular Formula	C860H1353N229O255S9
Molecular Weight	Approx. 19,271 Da
Synonyms	rIFN-α2b; Recombinant Interferon α-2b; IFN α-2b; Interferon alfa-2b (recombinant); Interferon α-2b; Intron A (Brand Name); Hu-IFN-alpha2; Leukocyte Interferon (recombinant); Interferon, leukocyte, human (recombinant α-2b)
EINECS	Contact for details

Quality Control

Our Interferon Alfa-2B is manufactured and tested to meet exacting standards for pharmaceutical applications. Each batch is subjected to a comprehensive battery of analytical tests including potency (antiviral assay), purity (HPLC), identity (peptide mapping, mass spectrometry), and stringent limits for endotoxins and host cell proteins. We provide full traceability and Certificates of Analysis (COA) that detail compliance with relevant specifications. Production can be aligned with cGMP guidelines for advanced therapeutic use upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be used immediately or stored at 2-8°C for short periods as validated. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under controlled humidity conditions to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Potency (Cell-based bioassay)	≥ 1.0 x 108 IU/mg
Purity (RP-HPLC)	≥ 98.0%
Related Proteins (HPLC)	≤ 2.0%
Endotoxin (LAL)	< 1.0 EU/mg
Moisture Content (KF)	≤ 2.0%
Biological Activity	Antiviral and antiproliferative activity confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.