Description

6-Cyano-2-Pyridine Carboxylic Acid Methyl Ester is a high-purity pyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex heterocyclic scaffolds, enabling the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine core provides essential bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying enzymatic pathways and protein function.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	6-Cyano-2-Pyridine Carboxylic Acid Methyl Ester
CAS No.	98436-83-0
Molecular Formula	C9H6N2O2
Molecular Weight	174.16 g/mol
Synonyms	Methyl 6-cyanopicolinate; 2-Pyridinecarboxylic acid, 6-cyano-, methyl ester; Methyl 6-cyano-2-pyridinecarboxylate; 6-Cyanopicolinic acid methyl ester; 2-Cyano-6-(methoxycarbonyl)pyridine; 6-Cyano-2-picolinic acid methyl ester; Methyl 2-cyano-6-pyridinecarboxylate; Picolinic acid, 6-cyano-, methyl ester
EINECS	Contact for details

Quality Control

Our 6-Cyano-2-Pyridine Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.