Description

3-Nitropyridine-4-Thiol is a versatile heterocyclic building block characterized by its reactive thiol and nitro functional groups. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), ligands for catalysis, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bioactive scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-withdrawing nitro group.
• Chemical Biology Probes: Utilized to create thiol-reactive probes and tags for studying protein interactions and cellular processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	3-Nitropyridine-4-Thiol
CAS No.	98382-93-5
Molecular Formula	C5H4N2O2S
Molecular Weight	156.16 g/mol
Synonyms	4-Mercapto-3-nitropyridine; 3-Nitro-4-pyridinethiol; 3-Nitro-4-mercaptopyridine; 4-Pyridinethiol, 3-nitro-; 3-Nitro-4-thiopyridinol; 4-Thiol-3-nitropyridine; 98382-93-5; 3-Nitro-4-sulfanylpyridine
EINECS	Contact for details

Quality Control

Our 3-Nitropyridine-4-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.