Description

(S)-(-)-3-Bromoisobutyric Acid Methyl Ester CAS NO 98190-85-3 is a high-purity chiral building block essential for the synthesis of optically active pharmaceutical intermediates and advanced materials. Its value lies in providing a stereochemically defined handle for introducing the 3-bromoisobutyryl moiety, a key functional group in controlled polymerization and medicinal chemistry. This compound is critically needed by research and development chemists in the pharmaceutical, agrochemical, and polymer science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing protease inhibitors and other small molecule therapeutics.
• ATRP Initiator: Serves as a specialized initiator in Atom Transfer Radical Polymerization (ATRP) for producing well-defined, stereoregular polymers and block copolymers.
• Agrochemical Synthesis: Used in the research and development of chiral agrochemicals, such as herbicides and fungicides, where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Employed as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Utilized in creating functionalized surfaces and advanced polymeric materials with specific architectural control.
• Chemical Biology Probes: Acts as a building block for synthesizing activity-based probes and other tools for studying enzymatic function and protein interactions.

Basic Information

Product Name	(S)-(-)-3-Bromoisobutyric Acid Methyl Ester
CAS No.	98190-85-3
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	(S)-Methyl 3-bromo-2-methylpropanoate; (S)-Methyl 3-bromoisobutyrate; (S)-(-)-Methyl 3-bromoisobutyrate; Methyl (S)-3-bromo-2-methylpropionate; (S)-3-Bromo-2-methylpropionic acid methyl ester; (S)-MBI; (S)-Methyl 3-bromo-2-methylpropanoate
EINECS	Contact for details

Quality Control

Our (S)-(-)-3-Bromoisobutyric Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.