Description

Boc-3-Cyclohexyl-L-Alanine Methyl Ester is a protected amino acid derivative, a crucial chiral building block for the synthesis of complex peptides and peptidomimetics. Its value lies in providing a chemically stable, enantiomerically pure intermediate that enables precise control over molecular architecture in advanced organic synthesis. This compound is essential for research and development chemists in the pharmaceutical, biotechnology, and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based therapeutics and novel drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the sterically hindered 3-cyclohexylalanine residue.
• Protease Inhibitor Development: Serves as a core component in the design and synthesis of inhibitors targeting specific enzymes.
• Agrochemical Research: Employed in the development of new peptide-inspired bioactive molecules for crop protection.
• Chemical Biology & Proteomics: Utilized as a tool compound for studying protein-protein interactions and modifying peptide structures.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	Boc-3-Cyclohexyl-L-Alanine Methyl Ester
CAS No.	98105-41-0
Molecular Formula	C₁₅H₂₇NO₄
Molecular Weight	285.38 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-3-cyclohexylpropanoic acid methyl ester; Methyl (2S)-2-[(tert-butoxycarbonyl)amino]-3-cyclohexylpropanoate; Boc-3-Cyclohexyl-L-Ala-OMe; N-Boc-3-cyclohexyl-L-alanine methyl ester; N-(tert-Butoxycarbonyl)-3-cyclohexyl-L-alanine methyl ester; Boc-Cyh-Ala-OMe; t-Boc-3-cyclohexyl-L-alanine methyl ester
EINECS	Contact for details

Quality Control

Our Boc-3-Cyclohexyl-L-Alanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and enantiomeric excess, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and other critical parameters are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.