Description

(2R,5R)-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5α-Acetic Acid is a high-purity, complex spirocyclic compound of significant interest in advanced organic synthesis. This specialized intermediate is valued for its unique stereochemistry and structural framework, which makes it a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex molecule synthesis.
• Agrochemical Synthesis: Used in the creation of advanced, biologically active compounds for crop protection and pest management.
• Fine Chemical Production: Serves as a crucial precursor in the manufacture of specialty chemicals requiring specific stereochemical configurations.
• Academic & Industrial Research: Employed in methodological studies and as a reference standard in stereoselective synthesis and catalysis research.
• Process Chemistry Development: Utilized for route scouting and optimization in pilot plants and commercial-scale chemical production.

Basic Information

Product Name	(2R,5R)-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5α-Acetic Acid
CAS No.	98103-38-9
Molecular Formula	C23H34O3
Molecular Weight	358.52 g/mol
Synonyms	5α-Cholan-24-oic Acid, 3β-Hydroxy-, (3β,5α)-; 3β-Hydroxy-5α-cholan-24-oic Acid; Allolithocholic Acid; iso-Lithocholic Acid; 5α-Lithocholic Acid; (3β,5α)-3-Hydroxycholan-24-oic Acid; 3β-Hydroxy-5α-cholanic Acid; NSC 83688
EINECS	Contact for details

Quality Control

Our production of (2R,5R)-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5α-Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. All materials are subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting full specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.