Description

Interferon Gamma 1 B is a potent cytokine and a key modulator of the immune system. This high-purity recombinant protein is essential for advanced research and therapeutic development targeting immune-related disorders. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on immunology, oncology, and infectious disease studies.

Application

• Immunotherapy Research: Investigation of immune cell activation, macrophage function, and antigen presentation pathways.
• Oncology Studies: Research into its role in tumor surveillance, anti-angiogenesis, and as an adjuvant in cancer vaccine development.
• Infectious Disease Models: Used in studies of host defense mechanisms against intracellular pathogens like bacteria and viruses.
• Autoimmune Disease Research: Exploration of its therapeutic potential and pathogenic role in conditions such as rheumatoid arthritis and multiple sclerosis.
• Cell Culture & Assay Development: Critical component in functional cell-based assays (e.g., antiviral assays) and for stimulating cell lines.
• Diagnostic Reagent Production: Serves as a standard or key reagent in the development of ELISA kits and other immunodiagnostic tools.
• Process Development & Scale-Up: Used in downstream process development for biomanufacturing of biologic drugs.

Basic Information

Product Name	Interferon Gamma 1 B
CAS No.	98059-61-1
Molecular Formula	C₈₆₁H₁₃₄₃N₂₂₉O₂₅₅S₉
Molecular Weight	Approx. 17,000 Da (monomer)
Synonyms	Interferon-gamma; IFN-γ; Immune Interferon; Type II Interferon; IFNG; Recombinant Human Interferon Gamma; Actimmune® (brand name); Avonex® (related); Fibroblast Interferon (historical); Macrophage-activating Factor; T-cell Interferon
EINECS	Contact for details

Quality Control

Our Interferon Gamma 1 B is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and safety, meeting the stringent requirements for research and development use. Certificates of Analysis (COA) detailing specifications such as purity by HPLC, endotoxin levels, biological activity, and sterility are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under controlled, dry conditions.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (SDS-PAGE)	≥ 95%
Purity (RP-HPLC)	≥ 98.0%
Biological Activity	≥ 1 x 10⁷ IU/mg
Endotoxin	< 1.0 EU/μg
Moisture Content (KF)	≤ 3.0%
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.