Description

4-Amino-5-Bromo-3-Methylpyridine is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and aminated structure makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science sectors, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, exploring new structure-activity relationships (SAR) and bioisosteres.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development-scale batches.

Basic Information

Product Name	4-Amino-5-Bromo-3-Methylpyridine
CAS No.	97944-43-9
Molecular Formula	C6H7BrN2
Molecular Weight	187.04 g/mol
Synonyms	5-Bromo-3-methylpyridin-4-amine; 3-Methyl-5-bromo-4-aminopyridine; 4-Amino-5-bromo-3-picoline; 5-Bromo-4-amino-3-methylpyridine; 3-Methyl-4-amino-5-bromopyridine; 97944-43-9; 4-Pyridinamine, 5-bromo-3-methyl-
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-5-Bromo-3-Methylpyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.