Description

4-Amino-5-Chloro-3-Picoline is a high-purity pyridine derivative and a versatile chemical building block essential for advanced synthesis. Its unique substitution pattern makes it a critical intermediate for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and gastrointestinal therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and other high-value specialty chemicals.
• Academic and Industrial Research: A valuable reagent for medicinal chemistry programs and process development in R&D laboratories.

Basic Information

Product Name	4-Amino-5-Chloro-3-Picoline
CAS No.	97944-42-8
Molecular Formula	C6H7ClN2
Molecular Weight	142.59 g/mol
Synonyms	5-Chloro-4-amino-3-picoline; 3-Picoline, 4-amino-5-chloro-; 4-Amino-5-chloro-3-methylpyridine; 5-Chloro-3-methyl-4-pyridinamine; 4-Amino-5-chloro-3-methylpyridine; 4-Amino-5-chloro-3-picoline; 3-Methyl-5-chloro-4-aminopyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-5-Chloro-3-Picoline is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Our products are supported by comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to guarantee supply consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.