Description

3-Bromo-2-Methylpyridine 1-Oxide is a versatile and high-value heterocyclic building block, specifically a halogenated pyridine N-oxide derivative. Its unique structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists engaged in creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine N-oxide moiety can enhance biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in fine chemical and polymer synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its modifiable electronic properties.
• Cross-Coupling Reactions: The bromine atom provides a handle for versatile metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to construct complex biaryl systems.
• Functionalization & Derivatization: The N-oxide group allows for directed functionalization at specific positions on the pyridine ring, enabling precise chemical modifications.

Basic Information

Product Name	3-Bromo-2-Methylpyridine 1-Oxide
CAS No.	97944-32-6
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	3-Bromo-2-picoline 1-Oxide; 2-Methyl-3-bromopyridine N-Oxide; 3-Bromo-2-methylpyridine N-Oxide; 3-Bromo-2-picoline N-Oxide; 2-Methyl-3-bromopyridine 1-Oxide; Pyridine, 3-bromo-2-methyl-, 1-oxide; 97944-32-6 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Methylpyridine 1-Oxide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.