Description

Lilopristone CAS NO 97747-88-1 is a synthetic steroid compound that functions as a selective progesterone receptor modulator (SPRM). This high-purity intermediate is critical for pharmaceutical research and development, particularly in the fields of endocrinology and reproductive health. It is primarily utilized by research institutions, pharmaceutical manufacturers, and contract development organizations for the synthesis of advanced therapeutic agents and in preclinical studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel progesterone receptor modulators and related steroid-based therapeutics.
• Endocrinology Research: Used as a reference standard and active compound in studies investigating progesterone receptor function and signaling pathways.
• Reproductive Health R&D: Employed in the development of potential treatments for conditions such as uterine fibroids, endometriosis, and hormone-dependent cancers.
• Biochemical Assay Development: Serves as a ligand in binding assays and screening tests to evaluate new chemical entities targeting the progesterone receptor.
• Academic Research: Utilized in university and institutional labs for fundamental studies in steroid hormone action and receptor biology.
• Preclinical Formulation: A starting material for creating formulations used in animal model studies to assess pharmacokinetics and efficacy.

Basic Information

Product Name	Lilopristone
CAS No.	97747-88-1
Molecular Formula	C31H41NO4
Molecular Weight	491.66 g/mol
Synonyms	11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17α-(3-hydroxypropyl)-13α-methyl-4,9-gonadien-3-one; ZK 98.734; ZK-98734; Lilopristone; (11β,13α,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-13-methyl-17-(3-hydroxypropyl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
EINECS	Contact for details

Quality Control

Our Lilopristone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets exacting standards for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.