Description

4-Isocyanatomethyl-6,7-methylenedioxycoumarin is a specialized heterocyclic building block featuring a reactive isocyanate group. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in advanced material and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or receptor binding.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging the coumarin scaffold's biological activity.
• Polymer Modification: Serves as a reactive monomer or cross-linking agent for introducing coumarin motifs into specialty polymers, coatings, or adhesives to impart unique optical or mechanical properties.
• Fluorescent Probe Synthesis: Employed in creating advanced fluorescent dyes and molecular probes for bioimaging and diagnostic applications due to the inherent fluorescence of the coumarin core.
• Material Science Research: Utilized in the development of advanced organic materials, such as organic light-emitting diodes (OLEDs) or sensors.
• Chemical Biology: Acts as a versatile handle for bioconjugation and labeling of biomolecules via the reactive isocyanate group.

Basic Information

Product Name	4-Isocyanatomethyl-6,7-Methylenedioxycoumarin
CAS No.	97744-89-3
Molecular Formula	C₁₂H₇NO₅
Molecular Weight	245.19 g/mol
Synonyms	4-(Isocyanatomethyl)-6,7-methylenedioxy-2H-chromen-2-one; 6,7-Methylenedioxycoumarin-4-methyl isocyanate; 4-Isocyanatomethyl-6,7-methylenedioxy-2H-1-benzopyran-2-one; 4-(Isocyanatomethyl)-6,7-methylenedioxycoumarin; NSC 339586; Coumarin derivative bearing isocyanate functionality
EINECS	Contact for details

Quality Control

Our 4-Isocyanatomethyl-6,7-methylenedioxycoumarin is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.