Description

Methyl 1-Benzyl-1,2,5,6-Tetrahydro-4-Hydroxynicotinate is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex pharmaceutical molecules, particularly those targeting neurological and cardiovascular pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel therapeutic agents.
• Neurological Research: Used in the development of compounds targeting nicotinic acetylcholine receptors for potential treatments of cognitive disorders.
• Cardiovascular Drug Development: Serves as a building block for molecules being investigated for hypertension and other cardiovascular conditions.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme mechanisms and protein interactions.
• Process Chemistry & Scale-Up: Utilized in process research and development (PR&D) for optimizing synthetic routes from lab to pilot scale.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in both university laboratories and industrial R&D departments exploring new chemical entities.

Basic Information

Product Name	Methyl 1-Benzyl-1,2,5,6-Tetrahydro-4-Hydroxynicotinate
CAS No.	97692-42-7
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	1-Benzyl-1,2,5,6-tetrahydro-4-hydroxy-3-pyridinecarboxylic acid methyl ester; Methyl 1-benzyl-4-hydroxy-1,2,5,6-tetrahydronicotinate; 4-Hydroxy-1-benzyl-1,2,5,6-tetrahydronicotinic acid methyl ester; 1-Benzyl-4-hydroxy-3-methoxycarbonyl-1,2,5,6-tetrahydropyridine; Nicotinic acid, 1,2,5,6-tetrahydro-4-hydroxy-1-benzyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 1-Benzyl-1,2,5,6-Tetrahydro-4-Hydroxynicotinate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.