Description

Glucosaminylmuramyl Dipeptide is a synthetic derivative of muramyl dipeptide (MDP), a key immunostimulatory component of bacterial peptidoglycan. This compound is of significant interest for its potent role in modulating innate immune responses and enhancing vaccine adjuvanticity. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors focused on novel immunotherapies, vaccine development, and immunological studies.

Application

• Vaccine Adjuvant Research: A key component in the development of next-generation vaccine formulations to enhance immunogenicity and efficacy.
• Immunomodulator Studies: Used in preclinical research to study the activation of NOD2 receptors and subsequent cytokine production.
• Drug Delivery Systems: Incorporated into liposomal or nanoparticle carriers for targeted immune stimulation.
• Innate Immunity Research: A critical tool for investigating signaling pathways of pattern recognition receptors (PRRs).
• Antitumor Therapy Development: Explored in experimental cancer immunotherapy protocols for its ability to stimulate anti-tumor immune responses.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Glucosaminylmuramyl Dipeptide
CAS No.	97590-38-0
Molecular Formula	C19H32N4O11
Molecular Weight	492.48 g/mol
Synonyms	GMDP; GlcN-MDP; N-Acetylglucosaminyl-N-acetylmuramyl-L-alanyl-D-isoglutamine; Glucosaminyl-N-acetylmuramyl dipeptide; Adjuvant peptide GMDP; L-Ala-γ-D-Glu-NH2 linked to MurNAc-GlcNAc; Immunostimulant GMDP; NOD2 ligand derivative
EINECS	Contact for details

Quality Control

Our Glucosaminylmuramyl Dipeptide is manufactured under strict quality systems suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing results from HPLC, NMR, and MS analysis is provided with every shipment to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.