Description

2-o-Acetyl-3-o-Allyl-4-o-Benzyl-6-o-tert-Butyldiphenylsilylglucopyranosyl Chloride is a sophisticated, multi-protected glycosyl donor, a critical intermediate in the synthesis of complex oligosaccharides and glycoconjugates. Its value lies in the strategic protection of hydroxyl groups, which allows for precise, sequential glycosylation reactions in carbohydrate chemistry. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel carbohydrate-based drugs, vaccines, and diagnostic agents.

Application

• Glycosylation Reagent: A key building block for the stereoselective synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and production of carbohydrate-based active pharmaceutical ingredients (APIs) for antiviral, anticancer, and antibacterial therapies.
• Glycoconjugate Synthesis: Essential for creating glycoproteins, glycolipids, and other biologically active conjugates for immunological studies and vaccine development.
• Carbohydrate Chemistry Research: A vital tool in academic and industrial R&D for exploring new synthetic pathways and carbohydrate structures.
• Biochemical Probe Development: Used to synthesize labeled or modified sugars for studying biological recognition and metabolic pathways.

Basic Information

Product Name	2-o-Acetyl-3-o-Allyl-4-o-Benzyl-6-o-tert-Butyldiphenylsilylglucopyranosyl Chloride
CAS No.	97576-48-2
Molecular Formula	C34H41ClO6Si
Molecular Weight	609.23 g/mol
Synonyms	1-Chloro-2-O-acetyl-3-O-allyl-4-O-benzyl-6-O-tert-butyldiphenylsilyl-α/β-D-glucopyranose; 2-O-Acetyl-3-O-allyl-4-O-benzyl-6-O-(tert-butyldiphenylsilyl)-D-glucopyranosyl Chloride; 6-O-TBDPS-2-O-Ac-3-O-Allyl-4-O-Bn-Glucosyl Chloride; TBDPS-Protected Glucosyl Chloride Donor; Glycosyl Chloride Intermediate 97576-48-2
EINECS	Contact for details

Quality Control

Every batch of our high-purity glycosylation intermediates is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR (¹H and ¹³C), and mass spectrometry to ensure structural identity, purity, and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and analytical results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Anomeric mixture)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.