Description

3-Exo-Benzyl 3-Hydroxy-8-Azabicyclo[3.2.1]Octane-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex bicyclic structure. This compound is of significant value in medicinal chemistry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of tropane alkaloid derivatives and other complex bioactive molecules.
• Medicinal Chemistry Research: Used in the research and development (R&D) of new drug candidates, especially for neurological and psychiatric applications.
• Process Chemistry: Serves as a critical chiral synthon in scalable API manufacturing processes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and novel synthetic pathways.

Basic Information

Product Name	3-Exo-Benzyl 3-Hydroxy-8-Azabicyclo[3.2.1]Octane-8-Carboxylate
CAS No.	96951-89-2
Molecular Formula	C15H19NO3
Molecular Weight	261.32 g/mol
Synonyms	8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-(phenylmethyl)-3-hydroxy-, exo-; 3-exo-Benzyl-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylic acid; 3-Benzyl-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate; 3-Hydroxy-3-benzyl-8-azabicyclo[3.2.1]octane-8-carboxylic acid; exo-3-Benzyl-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate; 8-ABCO derivative; Tropane alkaloid intermediate.
EINECS	Contact for details

Quality Control

Our 3-Exo-Benzyl 3-Hydroxy-8-Azabicyclo[3.2.1]Octane-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with complete traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (exo-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.