Description

Isopropenyl p-Nitrophenyl Carbonate is a specialized, high-purity chemical reagent primarily used as a versatile building block in organic synthesis. This compound is valued for its role as a reactive carbonate ester, facilitating the introduction of the p-nitrophenoxycarbonyl group under mild conditions. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the synthesis of active pharmaceutical ingredients (APIs), prodrugs, and advanced polymers.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of carbamate prodrugs and for the protection of amine functionalities during complex multi-step API manufacturing.
• Peptide Chemistry: Used as a coupling agent or activating reagent for the introduction of carbonate protecting groups in solid-phase and solution-phase peptide synthesis.
• Polymer Science: Serves as a monomer or cross-linking agent in the production of specialized polycarbonates and functional polymeric materials with tailored properties.
• Agrochemical Synthesis: Intermediate in the manufacture of certain herbicides, fungicides, and insecticides where the carbonate moiety is integral to biological activity.
• Bioconjugation: Useful for labeling biomolecules (e.g., proteins, antibodies) with reporter groups or drugs in biopharmaceutical research and diagnostics.
• Chemical Research: A valuable tool for academic and industrial R&D in developing new synthetic methodologies and novel organic compounds.

Basic Information

Item	Details
Product Name	Isopropenyl p-Nitrophenyl Carbonate
CAS No.	96916-42-6
Molecular Formula	C10H9NO5
Molecular Weight	223.18 g/mol
Synonyms	p-Nitrophenyl Isopropenyl Carbonate; 4-Nitrophenyl Isopropenyl Carbonate; Isopropenyl 4-Nitrophenyl Carbonate; 1-Methylvinyl 4-Nitrophenyl Carbonate; Carbonochloridic Acid, 1-Methylethenyl Ester, 4-Nitrophenyl Ester; IPNPC; (1-Methylvinyl) 4-nitrophenyl carbonate
EINECS	Contact for details

Quality Control

Our Isopropenyl p-Nitrophenyl Carbonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is accompanied by a comprehensive Certificate of Analysis (COA). The COA provides detailed results for identity, purity, and impurity profiles, typically determined by HPLC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.