Description

3Beta-Hydroxy-5-Cholestene 3-[6-(1-Pyrene)Hexanoate] is a high-purity, synthetic sterol derivative that serves as a critical intermediate and research reagent. This compound is valued for its unique molecular architecture, combining a cholesterol backbone with a pyrene fluorophore, which enables advanced applications in material science and analytical chemistry. It is primarily utilized by research institutions and industrial R&D departments specializing in fluorescence labeling, membrane biophysics, and the development of liquid crystal materials.

Application

• Fluorescent Probe and Labeling Agent: Used as a molecular probe in fluorescence spectroscopy and microscopy to study membrane dynamics, lipid rafts, and protein-lipid interactions due to the pyrene moiety's excellent photophysical properties.
• Advanced Material Synthesis: Serves as a key building block (mesogen) in the research and development of sterol-based liquid crystals and other functional organic materials.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to cholesterol metabolism and sterol-processing pathways.
• Analytical Standard: Used as a certified reference material (CRM) or internal standard in chromatographic (HPLC, GC) and mass spectrometric analyses for sterol quantification.
• Pharmaceutical Intermediate: Acts as a sophisticated synthetic intermediate in the research phase for novel therapeutic agents targeting lipid-related disorders.

Basic Information

Product Name	3Beta-Hydroxy-5-Cholestene 3-[6-(1-Pyrene)Hexanoate]
CAS No.	96886-70-3
Molecular Formula	C53H74O3
Molecular Weight	759.16 g/mol
Synonyms	Cholesteryl 6-(1-Pyrenyl)hexanoate; 3β-Hydroxycholest-5-ene 3-(6-pyren-1-ylhexanoate); Pyrene-labeled cholesterol; 1-Pyrenehexanoic Acid Cholesteryl Ester; 5-Cholesten-3β-ol, 3-(6-(1-Pyrenyl)hexanoate); Cholesterol Pyrene Derivative; Fluorescent Cholesterol Ester
EINECS	Contact for details

Quality Control

Our 3Beta-Hydroxy-5-Cholestene 3-[6-(1-Pyrene)Hexanoate] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and specific impurities. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under an inert atmosphere (e.g., argon or nitrogen) after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to pale yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.