Description

(E)-3-(2,3-Dihydro-1,4-Benzodioxin-6-Yl)-1-(5-Methoxy-2-Phenylmethoxyphenyl)Prop-2-En-1-One is a high-purity, non-racemic chiral compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its complex molecular architecture, featuring a benzodioxin core and a chalcone-like structure, which makes it an essential building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities for therapeutic applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct molecules with specific stereochemistry and functional groups.
• Material Science Research: Potential precursor for the development of specialty polymers or organic electronic materials due to its conjugated system.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	(E)-3-(2,3-Dihydro-1,4-Benzodioxin-6-Yl)-1-(5-Methoxy-2-Phenylmethoxyphenyl)Prop-2-En-1-One
CAS No.	96755-19-0
Molecular Formula	C25H22O5
Molecular Weight	402.44 g/mol
Synonyms	1-(5-Methoxy-2-(phenylmethoxy)phenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-propen-1-one; (E)-1-[5-Methoxy-2-(benzyloxy)phenyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-en-1-one; 96755-19-0; Chalcone derivative bearing benzodioxin and benzyloxy groups; 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-[5-methoxy-2-(phenylmethoxy)phenyl]prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our production of (E)-3-(2,3-Dihydro-1,4-Benzodioxin-6-Yl)-1-(5-Methoxy-2-Phenylmethoxyphenyl)Prop-2-En-1-One adheres to stringent quality management systems to ensure batch-to-batch consistency and traceability. The material is characterized and released based on comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support development and commercial projects with material produced under quality agreements and can supply grades suitable for research use through to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.