Description

1-Methyl-3-Trimethylsilylindole CAS NO 96694-00-7 is a versatile organosilicon-protected indole derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the trimethylsilyl (TMS) group, which acts as a protective and directing moiety, enabling selective functionalization of the indole core that is otherwise challenging. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for indole-based alkaloids and receptor-targeted molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the indole scaffold provides specific biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport or emissive layer materials in electronic displays and lighting.
• Material Science Research: Employed in the creation of novel polymers, liquid crystals, and functional organic materials with tailored properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organometallic chemistry and cross-coupling reactions.
• Fine Chemical Production: Intermediate for the manufacture of dyes, pigments, and other specialty chemicals requiring a functionalized indole structure.

Basic Information

Product Name	1-Methyl-3-Trimethylsilylindole
CAS No.	96694-00-7
Molecular Formula	C₁₂H₁₇NSi
Molecular Weight	203.36 g/mol
Synonyms	1-Methyl-3-(trimethylsilyl)-1H-indole; 3-(Trimethylsilyl)-1-methylindole; 1H-Indole, 1-methyl-3-(trimethylsilyl)-; N-Methyl-3-trimethylsilylindole; 1-Methyl-3-TMS-indole; 3-TMS-1-methylindole; Indole, 1-methyl-3-trimethylsilyl-; 96694-00-7
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Trimethylsilylindole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.