Description

(3'Aalpha,4'Alpha,5'Beta,6'Aalpha)-5'-[[(tert-Butyl)Dimethylsilyl]Oxy]Hexahydrospiro[1,3-Dioxolane-2,2'(1'H)-Pentalene]-4'-Methanol is a sophisticated, high-purity organic intermediate featuring a protected alcohol group, making it a critical building block in advanced synthetic chemistry. Its value lies in its precise stereochemistry and functional group protection, which enables efficient, multi-step synthesis of complex target molecules with high selectivity. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, including complex natural product analogs and targeted small molecules.
• Process Chemistry: Used in the scalable synthesis of advanced intermediates where the tert-butyldimethylsilyl (TBDMS) protecting group is required for selective reaction sequences.
• Asymmetric Synthesis: Employed in stereoselective transformations to construct complex molecular architectures with defined three-dimensional configurations.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals, agrochemicals, and high-performance materials requiring specific stereocenters.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and for producing reference standards in analytical laboratories.

Basic Information

Item	Information
Product Name	(3'Aalpha,4'Alpha,5'Beta,6'Aalpha)-5'-[[(tert-Butyl)Dimethylsilyl]Oxy]Hexahydrospiro[1,3-Dioxolane-2,2'(1'H)-Pentalene]-4'-Methanol
CAS No.	96648-15-6
Molecular Formula	C19H34O4Si
Molecular Weight	354.56 g/mol
Synonyms	5'-O-(tert-Butyldimethylsilyl)hexahydrospiro[1,3-dioxolane-2,2'-pentalene]-4'-methanol (stereoisomer); TBDMS-protected spiro-pentalene methanol derivative; (3'a,4'a,5'β,6'a)-5'-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydrospiro[1,3-dioxolane-2,2'(1'H)-pentalene]-4'-methanol; Hexahydrospiro[1,3-dioxolane-2,2'-pentalene]-4'-methanol, 5'-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (3'a,4'a,5'β,6'a)-; CAS 96648-15-6
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity suitable for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.