Description

1-Boc-D-Tryptophan Methyl Ester is a protected amino acid derivative essential for advanced peptide synthesis. This high-purity chiral building block is critical for researchers and manufacturers requiring precise stereochemical control in their processes. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of complex peptide-based drugs and APIs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-tryptophan residues with Boc (tert-butoxycarbonyl) protection.
• Biochemical Research: Serves as a critical reagent in proteomics research and for studying enzyme-substrate interactions.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for drug discovery and screening.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in the preparation of other non-natural amino acids and chiral compounds.

Basic Information

Product Name	1-Boc-D-Tryptophan Methyl Ester
CAS No.	96572-82-6
Molecular Formula	C19H24N2O4
Molecular Weight	344.41 g/mol
Synonyms	D-Tryptophan, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; (R)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(1H-indol-3-yl)propanoate; Boc-D-Trp-OMe; N-Boc-D-tryptophan methyl ester; N-tert-Butoxycarbonyl-D-tryptophan methyl ester; Methyl N-Boc-D-tryptophanate; Boc-D-Tryptophan Methyl Ester; (R)-Methyl 2-(tert-butoxycarbonylamino)-3-(1H-indol-3-yl)propanoate
EINECS	Contact for details

Quality Control

Our 1-Boc-D-Tryptophan Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.