Description

Ethyl 2,6-Dichloro-5-Fluoro-Pyridine-3-Acetoacetate is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel fluorinated drug candidates, particularly in antiviral and antibacterial research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the dichloro-fluoro-pyridine scaffold imparts specific biological activity.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic compounds in academic and industrial labs.
• Material Science Precursor: Potential intermediate in the synthesis of specialty chemicals and functional materials requiring halogenated aromatic systems.

Basic Information

Product Name	Ethyl 2,6-Dichloro-5-Fluoro-Pyridine-3-Acetoacetate
CAS No.	96568-04-6
Molecular Formula	C11H10Cl2FNO3
Molecular Weight	294.11 g/mol
Synonyms	Ethyl 2,6-dichloro-5-fluoronicotinoacetate; 3-Acetoacetic acid, 2,6-dichloro-5-fluoropyridine, ethyl ester; Ethyl (2,6-dichloro-5-fluoropyridin-3-yl)acetoacetate; 2,6-Dichloro-5-fluoro-3-pyridineacetic acid ethyl ester; Acetoacetic acid, (2,6-dichloro-5-fluoro-3-pyridyl)-, ethyl ester; 96568-04-6; Ethyl 2,6-dichloro-5-fluoro-3-pyridylacetoacetate
EINECS	Contact for details

Quality Control

Our Ethyl 2,6-Dichloro-5-Fluoro-Pyridine-3-Acetoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.