Description

Ethyl 4-Chloro-3-formyl-5,6-dihydro-2H-pyridine-1-carboxylate is a high-value, multi-functional heterocyclic building block primarily used in advanced organic synthesis. Its molecular structure, featuring both an aldehyde and a chloro substituent on a partially saturated pyridine ring, makes it a versatile precursor for constructing complex nitrogen-containing scaffolds. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of central nervous system (CNS) agents, anti-infectives, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactive sites to create compounds with specific biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Precursor: The formyl and chloro groups allow for further functionalization to create specialized ligands for metal catalysis or organocatalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Ethyl 4-Chloro-3-formyl-5,6-dihydro-2H-pyridine-1-carboxylate
CAS No.	96507-72-1
Molecular Formula	C9H10ClNO3
Molecular Weight	215.63 g/mol
Synonyms	1-Carbethoxy-4-chloro-3-formyl-1,2,3,6-tetrahydropyridine; Ethyl 4-chloro-3-formyl-1,2,3,6-tetrahydropyridine-1-carboxylate; 4-Chloro-3-formyl-1,2,3,6-tetrahydropyridine-1-carboxylic Acid Ethyl Ester; 1,2,3,6-Tetrahydro-4-chloro-3-formylpyridine-1-carboxylic Acid Ethyl Ester; 4-Chloro-3-formyl-5,6-dihydro-2H-pyridine-1-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-Chloro-3-formyl-5,6-dihydro-2H-pyridine-1-carboxylate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.