Description

Pyridine, 3-Chloro-2-Ethynyl- (9Ci) is a specialized halogenated and alkynylated pyridine derivative, serving as a high-value synthetic building block. Its molecular structure, featuring both chloro and ethynyl substituents, makes it a versatile intermediate for constructing complex heterocyclic systems and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis and discovery programs. Its precise reactivity profile enables the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its pyridine core provides bioactivity.
• Material Science Research: Serves as a precursor for developing functional organic materials, including ligands for catalysis and monomers for specialty polymers.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new coupling reactions and heterocyclic chemistry.
• Ligand Synthesis: Used to create sophisticated ligands for metal-organic frameworks (MOFs) and catalytic complexes.

Basic Information

Product Name	Pyridine, 3-Chloro-2-Ethynyl- (9Ci)
CAS No.	96439-98-4
Molecular Formula	C7H4ClN
Molecular Weight	137.57 g/mol
Synonyms	3-Chloro-2-ethynylpyridine; 2-Ethynyl-3-chloropyridine; 3-Chloro-2-ethynyl-pyridine; 3-Chloro-2-pyridylacetylene; 2-(Chloro)ethynyl-3-pyridine; 3-Chloro-2-(1-ethynyl)pyridine
EINECS	Contact for details

Quality Control

Our Pyridine, 3-Chloro-2-Ethynyl- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and GC-MS, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for research and development materials, ensuring reliable performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.