Description

8-Benzyloxy-2-Methyl-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate belonging to the imidazopyridine class of heterocyclic compounds. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and inflammatory pathways. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of new drug candidates, especially those with imidazopyridine scaffolds.
• Neurological Drug Research: Used in the development of compounds targeting GABAA receptor subtypes for potential anxiolytic, sedative, or sleep disorder treatments.
• Anti-inflammatory Agent Synthesis: Serves as a core structure for creating molecules with potential anti-inflammatory and analgesic properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing chemical probes and tool compounds to study biological systems.
• Process Chemistry & Scale-Up: Used in route scouting, optimization, and pilot-scale synthesis for new chemical entities (NCEs).
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and development services for clients.

Basic Information

Product Name	8-Benzyloxy-2-Methyl-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	96428-50-1
Molecular Formula	C18H18N2O3
Molecular Weight	310.35 g/mol
Synonyms	Ethyl 8-(benzyloxy)-2-methylimidazo[1,2-a]pyridine-3-carboxylate; 8-Benzyloxy-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-3-carboxylic acid, 8-(phenylmethoxy)-2-methyl-, ethyl ester; Ethyl 2-methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-carboxylate; 96428-50-1; UNII-9F4YVU3I4P
EINECS	Contact for details

Quality Control

Our 8-Benzyloxy-2-Methyl-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.